CHEMBL427844


SMILES CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)c1
InChIKey YWMJHCFRFHOSCO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 554.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pKi 10.0 10.0 10.0 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 6.3 6.3 6.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pIC50 9.4 9.4 9.4 ChEMBL
EP4 PE2R4 Human Prostanoid A pIC50 6.8 6.8 6.8 ChEMBL
TP TA2R Human Prostanoid A pIC50 8.6 8.6 8.6 ChEMBL