CHEMBL431943


SMILES O=C1CC2(CCCCC2)CC(=O)N1CCN1CCN(c2ccccc2Cl)CC1
InChIKey NEUNGUZCDMOARR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 403.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 8.54 8.54 8.54 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.24 7.24 7.24 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.38 6.38 6.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database