CHEMBL1258494


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc(C)ccc2C)CC1
InChIKey AAYMNPGQEZYHNE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 395.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.68 5.68 5.68 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.64 7.64 7.64 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.33 8.33 8.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.66 7.71 7.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database