CHEMBL4570584


SMILES Cc1ccccc1OCc1nc(N)nc(N2CCN(C)CC2)n1
InChIKey WBEGSSSQQIUZRQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 314.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.29 6.29 6.29 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.06 7.06 7.06 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.76 4.76 4.76 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.85 4.85 4.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.37 5.37 5.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database