CHEMBL458554


SMILES COc1cccc(N2CCN(CCCCNC(=O)c3ccc4nonc4c3)CC2)c1
InChIKey NUEKBJSFUOTLCO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 409.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.77 6.77 6.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.0 7.0 7.0 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.77 6.77 6.77 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database