CHEMBL4593671


SMILES COc1ccc2[nH]cc(CCNCc3ccc(-c4ccc(Cl)cc4)o3)c2c1
InChIKey VGKVYVYBJMIGOD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 380.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.66 5.66 5.66 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.17 7.17 7.17 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.66 6.66 6.66 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database