Chembl459659

Chemical Properties

SMILES CC(C)(C)c1ccc(-c2nc3c(N4CCN(Cc5cccc6[nH]c(=S)[nH]c56)CC4)cccc3[nH]2)cc1
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight 496.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey LMDJCZQDFNSVLY-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pIC50 6.62 6.79 6.96 ChEMBL
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 7.85 8.03 8.21 ChEMBL