CHEMBL4597531


SMILES CCCN(CCCCNC(=O)c1cc2ccccc2[nH]1)CC1CC1c1cc(F)ccc1OC
InChIKey GVNRTSAPTNNIPL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 451.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.1 6.1 6.1 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.06 6.06 6.06 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.42 6.42 6.42 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.17 7.17 7.17 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.95 7.95 7.95 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.29 6.29 6.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database