2MeSAMP


SMILES CSc1nc(N)c2c(n1)n(cn2)[C@@H]1O[C@@H]([C@H]([C@H]1O)O)COP(=O)(O)O
InChIKey XVTFTCNRRAQHEQ-KQYNXXCUSA-N

Chemical properties

Hydrogen bond acceptors 11
Hydrogen bond donors 5
Rotatable bonds 5
Molecular weight (Da) 393.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pKd 6.6 7.7 8.8 Guide to Pharmacology
ghrelin GHSR Rat Ghrelin A pKi 8.8 8.8 8.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pEC50 8.71 8.71 8.71 Guide to Pharmacology