CHEMBL44403


SMILES COc1cccc(OC)c1OCCNCC1CC(c2ccccc2)c2ccccc2C1=O
InChIKey UZPNDQMXOWZSMG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 431.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 8.7 8.7 8.7 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 7.58 7.58 7.58 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 8.91 8.91 8.91 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 9.35 9.41 9.46 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.74 9.74 9.74 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.6 9.6 9.6 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.96 7.96 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database