CHEMBL4441655


SMILES CN1CCN(c2nc(N)nc(CS(=O)(=O)c3ccccc3Cl)n2)CC1
InChIKey WWPMYLXEYGNGDR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 382.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.01 4.01 4.01 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.45 5.45 5.45 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.94 4.94 4.94 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.3 4.3 4.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database