Chembl4647332

Chemical Properties

SMILES COC(=O)CNC(=O)[C@H](CCc1ccccc1)NC(=O)c1cc(-c2c(OC)cccc2OC)n(CC(C)C)n1
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 13
Molecular weight 536.3

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey UFYKBWPLFPOPMA-NRFANRHFSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
apelin APJ Human Apelin A pEC50 5.51 6.27 7.68 ChEMBL
apelin APJ Human Apelin A pKi 6.73 6.73 6.73 ChEMBL