CHEMBL4449148


SMILES O=[N+]([O-])c1ccccc1N1CCN(CCCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
InChIKey ULMWAKXWMKUGMX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 494.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.31 6.31 6.31 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.32 6.32 6.32 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.58 6.58 6.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database