CHEMBL4636165


SMILES C#CCOc1c(OC)cc2c3c1-c1cc(NC(=O)CCC)ccc1CC3N(C)CC2
InChIKey RUGBLRYISYKONW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 404.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.18 6.18 6.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database