GLPG1205
| SMILES | O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1c2ccc(c1)C#CC1CC1 |
| InChIKey | IRBAWVGZNJIROV-SFHVURJKSA-N |
Chemical properties
| Hydrogen bond acceptors | 6 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 3 |
| Molecular weight (Da) | 378.2 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GPR84 | GPR84 | Human | A orphans | A | pKi | 7.52 | 7.52 | 7.52 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GPR84 | GPR84 | Human | A orphans | A | pIC50 | 7.0 | 9.0 | 11.0 | Guide to Pharmacology |
| GPR84 | GPR84 | Human | A orphans | A | pEC50 | 4.03 | 5.16 | 6.21 | ChEMBL |
| GPR84 | GPR84 | Human | A orphans | A | pIC50 | 6.95 | 8.69 | 11.0 | ChEMBL |