CHEMBL471340


SMILES CNCC(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2C(O)CC(C)C)CC1
InChIKey AXBQVTBYSIEJPU-XQZUBTRRSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 534.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKi 5.75 5.75 5.75 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.6 5.6 5.6 ChEMBL
MC4 MC4R Human Melanocortin A pKi 6.3 7.19 8.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pIC50 6.38 6.38 6.38 ChEMBL