CHEMBL4471755


SMILES COc1ccc(-c2c3n(c(=O)n(CCCCN4CCCC(c5c[nH]c6ccc(OC)cc56)C4)c2=O)CCCC3)cc1
InChIKey FMIGXIISTXPFJX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 556.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.74 5.74 5.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database