CHEMBL470790
SMILES | N=C(NCCCc1c[nH]cn1)NC(=O)CCc1ccccc1 |
InChIKey | PUDXEVBPMISDEU-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 4 |
Rotatable bonds | 7 |
Molecular weight (Da) | 299.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H1 | HRH1 | Guinea pig | Histamine | A | pKd | 5.67 | 5.67 | 5.67 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H4 | HRH4 | Human | Histamine | A | pEC50 | 7.8 | 7.8 | 7.8 | ChEMBL |
H2 | HRH2 | Human | Histamine | A | pEC50 | 7.2 | 7.2 | 7.2 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pEC50 | 8.6 | 8.6 | 8.6 | ChEMBL |