CHEMBL472677
SMILES | O=C1N(CC2CC2)CN(c2ccccc2)C12CCN(C(c1ccccc1)c1ccccc1)CC2 |
InChIKey | DFUWOFTVSMOGGO-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 0 |
Rotatable bonds | 6 |
Molecular weight (Da) | 451.3 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
NOP | OPRX | Human | Opioid | A | pKi | 7.08 | 7.08 | 7.08 | ChEMBL |
δ | OPRD | Human | Opioid | A | pKi | 5.27 | 5.27 | 5.27 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 6.2 | 6.2 | 6.2 | ChEMBL |
μ | OPRM | Human | Opioid | A | pKi | 5.28 | 5.28 | 5.28 | ChEMBL |
NOP | OPRX | Human | Opioid | A | pKi | 7.08 | 7.08 | 7.08 | PDSP Ki database |
δ | OPRD | Human | Opioid | A | pKi | 5.27 | 5.27 | 5.27 | PDSP Ki database |
μ | OPRM | Human | Opioid | A | pKi | 5.28 | 5.28 | 5.28 | PDSP Ki database |
κ | OPRK | Human | Opioid | A | pKi | 6.2 | 6.2 | 6.2 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |