CHEMBL473280
SMILES | CC(C)N(CCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O)C(C)C |
InChIKey | OYYKUZKRRODNKD-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 7 |
Molecular weight (Da) | 516.4 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
κ | OPRK | Human | Opioid | A | pKi | 7.07 | 7.07 | 7.07 | ChEMBL |
μ | OPRM | Human | Opioid | A | pKi | 7.09 | 7.09 | 7.09 | ChEMBL |
NOP | OPRX | Human | Opioid | A | pKi | 8.17 | 8.17 | 8.17 | PDSP Ki database |
δ | OPRD | Human | Opioid | A | pKi | 5.53 | 5.53 | 5.53 | PDSP Ki database |
κ | OPRK | Human | Opioid | A | pKi | 7.07 | 7.07 | 7.07 | PDSP Ki database |
μ | OPRM | Human | Opioid | A | pKi | 7.09 | 7.09 | 7.09 | PDSP Ki database |
δ | OPRD | Human | Opioid | A | pKi | 5.53 | 5.53 | 5.53 | ChEMBL |
NOP | OPRX | Human | Opioid | A | pKi | 8.17 | 8.17 | 8.17 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |