CHEMBL474687


SMILES CCNCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O
InChIKey SPEMYEUTUHZLSU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 460.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.8 8.8 8.8 ChEMBL
δ OPRD Human Opioid A pKi 5.68 5.68 5.68 ChEMBL
κ OPRK Human Opioid A pKi 7.41 7.41 7.41 ChEMBL
μ OPRM Human Opioid A pKi 7.43 7.43 7.43 ChEMBL
NOP OPRX Human Opioid A pKi 8.8 8.8 8.8 PDSP Ki database
δ OPRD Human Opioid A pKi 5.69 5.69 5.69 PDSP Ki database
κ OPRK Human Opioid A pKi 7.41 7.41 7.41 PDSP Ki database
μ OPRM Human Opioid A pKi 7.43 7.43 7.43 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database