CHEMBL4532741


SMILES COc1cccc(N2CCN(CCCCCCN3C(=O)c4cccc5cccc(c45)C3=O)CC2)c1
InChIKey KQYVDEWSKFDTLI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 471.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.43 6.43 6.43 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.46 6.46 6.46 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.33 7.33 7.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database