CHEMBL476722


SMILES COc1ccccc1N1CCN(CCCCCCSc2nc3ccccc3o2)CC1
InChIKey UAQAANDOLMXUHK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 6.04 6.04 6.04 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.33 7.33 7.33 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.89 9.09 9.28 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.89 9.09 9.28 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 6.04 6.04 6.04 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database