CHEMBL4783987


SMILES Fc1ccc(CCCCN2CCN(c3ccc(-c4ccccc4)cn3)CC2)cc1
InChIKey VAVQKONBNVLSBI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 389.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.65 5.65 5.65 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.83 5.83 5.84 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.83 6.83 6.83 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.68 5.69 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database