CHEMBL4789472


SMILES O=C(CCCN1C2CCC1CN(c1ccc(Cl)cn1)C2)c1ccc(F)cc1
InChIKey UPBSKELQKAHWLX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 387.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.48 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.87 5.87 5.87 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.11 7.11 7.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.29 7.29 7.29 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.9 5.9 5.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database