CHEMBL4581256


SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
InChIKey KUSKRNBCFWEDGT-DSCYDBDCSA-N

Chemical properties

Hydrogen bond acceptors 19
Hydrogen bond donors 25
Rotatable bonds 51
Molecular weight (Da) 1589.9

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y4 NPY4R Human Neuropeptide Y A pKi 7.92 7.92 7.92 ChEMBL
Y5 NPY5R Human Neuropeptide Y A pKi 6.66 6.66 6.66 ChEMBL
Y1 NPY1R Human Neuropeptide Y A pKi 5.85 5.85 5.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y4 NPY4R Human Neuropeptide Y A pEC50 6.54 6.67 6.8 ChEMBL