CHEMBL479026


SMILES c1cnc(N2CCN(CCCSc3nc4ccccc4s3)CC2)nc1
InChIKey PEPMTRGKCCXQQJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 371.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.27 6.27 6.27 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.6 8.6 8.6 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.6 8.6 8.6 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database