Chembl48134

Chemical Properties

SMILES COc1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(C)c1
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight 441.0

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey JAISZXOUESMARL-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETB EDNRB Human Endothelin A pIC50 4.85 4.85 4.85 ChEMBL
ETA EDNRA Human Endothelin A pIC50 8.59 8.59 8.59 ChEMBL