CHEMBL4595600


SMILES CCCN(CCCCNC(=O)c1ccc(-c2ccccn2)cc1)CC1CC1c1ccc(C(F)(F)F)cc1
InChIKey QDADEDFRUNQJKV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 509.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.11 5.11 5.11 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.66 5.66 5.66 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.85 5.85 5.85 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.63 5.63 5.63 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.63 7.63 7.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database