CHEMBL460402


SMILES CN(CCC=C1c2ccccc2CCc2ccccc21)C(=O)c1ccc(OCCCN2CCCCC2)cc1
InChIKey DFBYKWKCUIKCPG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 508.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 6.16 6.16 6.16 ChEMBL
H3 HRH3 Human Histamine A pKi 8.46 8.46 8.46 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.61 6.61 6.61 ChEMBL
H3 HRH3 Human Histamine A pKi 8.46 8.46 8.46 PDSP Ki database
D1 DRD1 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
H1 HRH1 Human Histamine A pKi 6.16 6.16 6.16 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.61 6.61 6.61 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database