CHEMBL483593


SMILES CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1CC=C(C#C[Si](C)(C)C)CC1
InChIKey YVKJVUJRJJSJAZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 486.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.42 5.42 5.42 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.16 7.16 7.16 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.36 8.36 8.36 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.44 6.55 6.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.44 6.55 6.66 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 8.36 8.36 8.36 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 7.16 7.16 7.16 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database