RP-52770


SMILES Clc1cccc(c1)NC(=O)c1ccn2c1CSC2c1cccnc1
InChIKey MJGVBIXLFIUPQU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 355.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A1 AA1R Human Adenosine A pKi 7.26 7.26 7.26 Guide to Pharmacology
A2A AA2AR Human Adenosine A pKi 5.0 5.0 5.0 Guide to Pharmacology
A2B AA2BR Human Adenosine A pKi 4.3 4.3 4.3 Guide to Pharmacology
A3 AA3R Human Adenosine A pKi 6.0 6.0 6.0 Guide to Pharmacology
A1 AA1R Human Adenosine A pKd 5.3 5.3 5.3 ChEMBL
A1 AA1R Human Adenosine A pKi 5.96 6.94 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database