CHEMBL4639970


SMILES FC(F)(F)CC1CN2CCNCc3cccc1c32
InChIKey RJTYUQILGKNDIK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 256.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.54 6.54 6.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 5.47 5.47 5.47 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.36 7.36 7.36 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 5.4 5.4 5.4 ChEMBL