GPCRdb

CHEMBL4858338

Agent/drug
Bioactivity

CHEMBL4858338

SMILES	Clc1ccc(-c2n[nH]cc2N2CCNCC2)cc1
InChIKey	RGVBFCBKZDWNNA-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	2
Molecular weight (Da)	262.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.92	6.92	6.92	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.54	5.54	5.54	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	6.59	6.59	6.59	ChEMBL
5-HT_5A	5HT5A	Human	5-Hydroxytryptamine	A	pKi	6.16	6.16	6.16	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	7.12	7.12	7.12	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	7.63	7.63	7.64	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pIC50	6.05	6.05	6.05	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL4858338

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.