CHEMBL4869389


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC[C@@H](C)c1ccccc1
InChIKey IQHAIFKWYGPTRN-GFCCVEGCSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 7
Molecular weight (Da) 374.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pKi 6.99 6.99 6.99 ChEMBL
H1 HRH1 Human Histamine A pKi 5.02 5.02 5.02 ChEMBL
H3 HRH3 Human Histamine A pKi 4.57 4.57 4.57 ChEMBL
H4 HRH4 Human Histamine A pKi 4.87 4.87 4.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database