CHEMBL1276247


SMILES C[C@@H](Oc1ccccc1-c1ccsc1)C1=NCCN1
InChIKey IAIZHDGEGFGNMO-LLVKDONJSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 272.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.15 6.15 6.15 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.5 6.5 6.5 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.78 6.78 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 7.0 7.0 7.0 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 5.5 5.5 5.5 ChEMBL