CHEMBL474447


SMILES N/C(=N\C(=O)Cc1c[nH]c2ccccc12)NCCCc1c[nH]cn1
InChIKey IACQTGSSMZJQPH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 324.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Guinea pig Histamine A pKd 7.41 7.41 7.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 7.72 7.72 7.72 ChEMBL
H2 HRH2 Human Histamine A pEC50 7.44 7.44 7.44 ChEMBL