CHEMBL492282


SMILES CC(C)c1ccccc1N1CCN(CCCCCC(=O)N2CCc3ccccc3C2)CC1
InChIKey QDZRLBZZELBOIJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 433.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.43 8.43 8.43 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.89 8.89 8.89 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.43 8.43 8.43 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 8.89 8.89 8.89 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database