CHEMBL497574


SMILES O=C1c2cc3ccccc3n2CCN1CCCCN1CCN(c2ccc(Cl)cc2Cl)CC1
InChIKey XLZXIDKEIKKBGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 470.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.37 5.37 5.37 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.64 6.64 6.64 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.49 8.49 8.49 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.49 8.49 8.49 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.37 5.37 5.37 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database