CHEMBL504349


SMILES CCC[C@H]1C(=O)N([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)CCN1C(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)[C@H](C)NC
InChIKey AHYGIWNTGDKMRR-SUAIOLNFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 12
Molecular weight (Da) 603.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 7.0 7.0 7.0 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.68 6.68 6.68 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.22 8.22 8.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 7.3 7.3 7.3 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 7.29 7.29 7.29 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 8.77 8.77 8.77 ChEMBL