GPCRdb

LOVASTATIN

Agent/drug
Bioactivity

LOVASTATIN

SMILES	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21
InChIKey	PCZOHLXUXFIOCF-BXMDZJJMSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	404.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

A₁	AA1R	Human	Adenosine	A	pKi	4.81	4.81	4.81	ChEMBL
A₁	AA1R	Human	Adenosine	A	pKi	8.32	8.32	8.32	Drug Central
NK₂	NK2R	Human	Tachykinin	A	pKi	5.03	5.03	5.03	ChEMBL
NK₂	NK2R	Human	Tachykinin	A	pKi	8.30	8.30	8.30	Drug Central

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

A₁	AA1R	Human	Adenosine	A	pIC50	4.57	4.57	4.57	ChEMBL
HCA₂	HCAR2	Human	Hydroxycarboxylic acid	A	pIC50	8.14	8.14	8.14	Drug Central
HCA₃	HCAR3	Human	Hydroxycarboxylic acid	A	pIC50	8.19	8.19	8.19	Drug Central
NK₂	NK2R	Human	Tachykinin	A	pIC50	4.55	4.55	4.55	ChEMBL
TSH	TSHR	Human	Glycoprotein hormone	A	Potency	4.40	4.40	4.40	ChEMBL

Showing 1 to 5 of 5 entries

LOVASTATIN

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.