CHEMBL4780536


SMILES COc1cc(N)c(Cl)cc1C(=O)CCC1CCN(CCNS(=O)(=O)c2ccc(N)c(Br)c2)CC1
InChIKey LGPOBVLZHCYRKV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 572.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 8.28 8.28 8.28 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.66 6.66 6.66 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database