CHEMBL514606
SMILES | CCCCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3)c3ccccc3)CC2)C1=O |
InChIKey | VFEHYWWZSNCIAC-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 0 |
Rotatable bonds | 7 |
Molecular weight (Da) | 453.3 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
NOP | OPRX | Human | Opioid | A | pKi | 7.24 | 7.24 | 7.24 | ChEMBL |
δ | OPRD | Human | Opioid | A | pKi | 4.23 | 4.23 | 4.23 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 6.11 | 6.11 | 6.11 | ChEMBL |
μ | OPRM | Human | Opioid | A | pKi | 5.07 | 5.07 | 5.07 | ChEMBL |
NOP | OPRX | Human | Opioid | A | pKi | 7.24 | 7.24 | 7.24 | PDSP Ki database |
δ | OPRD | Human | Opioid | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
μ | OPRM | Human | Opioid | A | pKi | 5.07 | 5.07 | 5.07 | PDSP Ki database |
κ | OPRK | Human | Opioid | A | pKi | 6.11 | 6.11 | 6.11 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |