AH6809
SMILES | CC(Oc1ccc2c(c1)oc1c(c2=O)cc(cc1)C(=O)O)C |
InChIKey | AQFFXPQJLZFABJ-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 1 |
Rotatable bonds | 3 |
Molecular weight (Da) | 298.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
DP1 | PD2R | Human | Prostanoid | A | pKi | 5.8 | 5.8 | 5.8 | Guide to Pharmacology |
EP1 | PE2R1 | Human | Prostanoid | A | pKi | 5.9 | 5.95 | 6.0 | Guide to Pharmacology |
EP2 | PE2R2 | Human | Prostanoid | A | pKi | 5.9 | 5.9 | 5.9 | Guide to Pharmacology |
EP3 | PE2R3 | Human | Prostanoid | A | pKi | 5.8 | 5.8 | 5.8 | Guide to Pharmacology |
EP1 | PE2R1 | Rat | Prostanoid | A | pKi | 5.9 | 5.9 | 5.9 | Guide to Pharmacology |
EP2 | PE2R2 | Rat | Prostanoid | A | pKi | 6.3 | 6.3 | 6.3 | Guide to Pharmacology |
EP2 | PE2R2 | Mouse | Prostanoid | A | pKi | 6.5 | 6.5 | 6.5 | Guide to Pharmacology |
EP2 | PE2R2 | Mouse | Prostanoid | A | pKi | 6.46 | 6.46 | 6.46 | PDSP Ki database |
EP4 | PE2R4 | Human | Prostanoid | A | pKi | 5.0 | 5.47 | 5.94 | PDSP Ki database |
EP3 | PE2R3 | Human | Prostanoid | A | pKi | 5.8 | 5.8 | 5.8 | PDSP Ki database |
IP | PI2R | Human | Prostanoid | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
DP1 | PD2R | Human | Prostanoid | A | pKi | 5.85 | 5.85 | 5.85 | PDSP Ki database |
DP1 | PD2R | Human | Prostanoid | A | pKi | 5.85 | 5.85 | 5.85 | ChEMBL |
EP1 | PE2R1 | Human | Prostanoid | A | pKi | 5.91 | 5.91 | 5.91 | PDSP Ki database |
EP1 | PE2R1 | Human | Prostanoid | A | pKi | 5.92 | 5.92 | 5.92 | ChEMBL |
EP2 | PE2R2 | Human | Prostanoid | A | pKi | 5.94 | 5.94 | 5.94 | ChEMBL |
EP3 | PE2R3 | Human | Prostanoid | A | pKi | 5.8 | 5.8 | 5.8 | ChEMBL |
FP | PF2R | Human | Prostanoid | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |