CHEMBL5178511


SMILES O=C(Cc1ccccc1)N[C@@H]1C[C@]23CCN(CC4CC4)[C@H](Cc4ccc(O)cc42)[C@]32CC[C@@H]1O2
InChIKey OHPZSCSFNDIFCZ-IFJBLKETSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 458.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 9.28 9.28 9.28 ChEMBL
κ OPRK Human Opioid A pKi 9.71 9.71 9.71 ChEMBL
μ OPRM Human Opioid A pKi 9.57 9.57 9.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.22 8.22 8.22 ChEMBL
κ OPRK Human Opioid A pEC50 8.51 8.51 8.51 ChEMBL
μ OPRM Human Opioid A pEC50 8.03 8.03 8.03 ChEMBL