GW842166
SMILES | ClC1=C(NC2=NC=C(C(=N2)C(F)(F)F)C(=O)NCC3CCOCC3)C=CC(=C1)Cl |
InChIKey | TWQYWUXBZHPIIV-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 2 |
Rotatable bonds | 5 |
Molecular weight (Da) | 448.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | Yes |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CB2 | CNR2 | Rat | Cannabinoid | A | pEC50 | 7.04 | 7.04 | 7.04 | ChEMBL |
CB2 | CNR2 | Human | Cannabinoid | A | pEC50 | 6.36 | 6.83 | 7.3 | ChEMBL |
CB2 | CNR2 | Human | Cannabinoid | A | pEC50 | 7.2 | 7.2 | 7.2 | Guide to Pharmacology |
CB2 | CNR2 | Rat | Cannabinoid | A | pEC50 | 7.04 | 7.04 | 7.04 | Guide to Pharmacology |