CHEMBL5187317


SMILES COc1ccccc1N1CCN(CCCCCNc2nc(N)nc(N)n2)CC1
InChIKey QWZAQKYTKIEATF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 386.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.02 6.02 6.02 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.18 5.18 5.18 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.19 5.19 5.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.42 7.42 7.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database