CHEMBL4803378


SMILES N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@@H](O)[C@@H]1CSc1ccccc1
InChIKey XMENKXPGVGTNAZ-STTOLWRSSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 323.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.62 6.62 6.62 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 5.67 5.67 5.67 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 5.69 5.69 5.69 ChEMBL