Chembl568307

Chemical Properties

SMILES O[C@@H]1[C@H](O)[C@@H]2C[C@@H]2[C@H]1n1cnc2c(NCc3cccc(I)c3)nc(F)nc21
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight 481.0

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey MHFWPUAKMSPBGS-JHOKLZQASA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A3 AA3R Human Adenosine A pKi 7.97 7.97 7.97 ChEMBL
A2A AA2AR Human Adenosine A pKi 5.4 5.4 5.4 ChEMBL
A1 AA1R Human Adenosine A pKi 6.29 6.29 6.29 ChEMBL