17-phenyl-ω-trinor-PGE2


SMILES OC(=O)CCC/C=C\C[C@H]1C(=O)C[C@H]([C@@H]1/C=C/[C@H](CCc1ccccc1)O)O
InChIKey FOBVMYJQWZOGGJ-XYRJXBATSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKd 7.7 7.7 7.7 Guide to Pharmacology
MC3 MC3R Human Melanocortin A pKd 8.3 8.3 8.3 Guide to Pharmacology
MC4 MC4R Human Melanocortin A pKd 9.5 9.5 9.5 Guide to Pharmacology
MC5 MC5R Human Melanocortin A pKd 8.5 8.5 8.5 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database