CHEMBL5222831
SMILES | Cc1nnc(CCCN/C(N)=N/C(=O)NCC(C)C2CCCCC2)s1 |
InChIKey | ZKKBZRDZTBXDKE-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 3 |
Rotatable bonds | 7 |
Molecular weight (Da) | 366.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H2 | HRH2 | Human | Histamine | A | pKi | 5.98 | 5.98 | 5.98 | ChEMBL |
H2 | HRH2 | Human | Histamine | A | pKd | 7.91 | 7.91 | 7.91 | ChEMBL |
H1 | HRH1 | Human | Histamine | A | pKi | 5.15 | 5.15 | 5.15 | ChEMBL |
H1 | HRH1 | Human | Histamine | A | pKd | 8.35 | 8.35 | 8.35 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKd | 8.52 | 8.52 | 8.52 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 4.94 | 4.94 | 4.94 | ChEMBL |
H4 | HRH4 | Human | Histamine | A | pKd | 7.8 | 7.8 | 7.8 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |